Tlhaloso
4-amino-5-methyl-2-hydroxypyridine ea rona ke karolo e ka sehloohong ea motsoako oa Finerenone, e leng mohanyetsi e mocha oa mineralocorticoid ea khethiloeng ka mokhoa o sa steroidal ea nang le bokhoni ba ho phekola mafu a pelo le a renal.Lisebelisoa tse ka bang teng.Motsoako ona ke karolo ea bohlokoa tlhahisong ea Finerenone, e etsang hore e be motsoako oa bohlokoa bakeng sa lik'hamphani tsa meriana le mekhatlo ea lipatlisiso.
Ho hloeka le boleng ba 4-amino-5-methyl-2-hydroxypyridine ea rona ha e bapisoe, ho netefatsa hore e loketse mekhahlelo eohle ea nts'etsopele le tlhahiso ea lithethefatsi.Re tsepamisitse maikutlo holim'a bokhabane le boqapi, re ntlafalitse mokhoa oa rona oa ho kopanya le oa tlhoekiso ho fana ka lihlahisoa tse fihlelang maemo a thata a indasteri ea meriana.
Boitlamo ba rona ba boleng bo atolohela karolong e 'ngoe le e 'ngoe ea ts'ebetso ea rona, ho tloha ho fumana thepa e tala ho isa ho tlhahiso le kabo.Re khomarela litekanyetso tse phahameng ka ho fetisisa tsa polokeho le ho lumellana ho netefatsa hore bareki ba rona ba fumana lihlahisoa tse finyellang litlhoko tse thata ka ho fetisisa tsa taolo.
Khetha Rona
JDK e na le lisebelisoa tsa tlhahiso ea maemo a pele le lisebelisoa tsa taolo ea boleng, tse netefatsang phepelo e tsitsitseng ea li-intermediate tsa API.Sehlopha sa litsebi se tiisetsa R&D ka sehlahisoa.Khahlanong le bobeli, re batla CMO & CDMO 'marakeng oa lapeng le oa machabeng.
