Khetha Rona
JDK e na le lisebelisoa tsa tlhahiso ea maemo a pele le lisebelisoa tsa taolo ea boleng, tse netefatsang phepelo e tsitsitseng ea li-intermediate tsa API.Sehlopha sa litsebi se tiisetsa R&D ka sehlahisoa.Khahlanong le bobeli, re batla CMO & CDMO 'marakeng oa lapeng le oa machabeng.
Tlhaloso ea Sehlahisoa
Motheong oa eona, 17-amino-10-oxy-3,6,12,15-tetraoxa-9-azaheptadecanoic acid ke motsoako o rarahaneng o nang le bokhoni bo boholo mefuteng e fapaneng ea likopo.Sebopeho sa eona sa limolek'hule le motsoako o ikhethang oa likarolo li etsa hore e be letlotlo la bohlokoa bakeng sa nts'etsopele ea lithethefatsi, biochemistry le boiteko bo amanang le saense.
E 'ngoe ea likarolo tse ka sehloohong tsa sehlahisoa sena ke ho feto-fetoha ha eona.17-Amino-10-oxy-3,6,12,15-tetraoxa-9-azaheptadecanoic acid e ka sebelisoa e le mohaho oa mohaho ha ho etsoa limolek'hule tse sa tšoaneng tsa bioactive, tse kang li-peptide le liprotheine.Lihlopha tsa eona tse sebetsang le tatellano ea li-amino acid li etsa hore ho be le phetoho e nepahetseng le e nepahetseng, e netefatsang boemo bo phahameng ba taolo le bo ikhethang moralong oa lithethefatsi.
Bafuputsi le bo-ramahlale mafapheng a bongaka le ho sibolla lithethefatsi ba tla rua molemo haholo ka ho kenyelletsa sehlahisoa sena lipatlisisong tsa bona.Lisebelisoa tse ka bang teng li tloha ho mekhoa e lebisitsoeng ea phepelo ea lithethefatsi ho ea ho nts'etsopele ea li-agent tse ncha tsa phekolo.Ka ho sebelisa thepa e ikhethang ea 17-amino-10-oxy-3,6,12,15-tetraoxa-9-azaheptadecanoic acid, lik'hamphani tsa meriana li ka qapa le ho theha mekhoa ea phekolo ea mafu a sa tšoaneng.
Ho phaella moo, ho tiea ha sehlahisoa ho tiisa botsitso le ho tšepahala tlas'a maemo a sa tšoaneng a liteko.Boima ba eona ba limolek'hule le sebopeho sa eona li entsoe ka hloko ho fana ka ho qhibiliha ka ho feletseng, ho lumella ho kopanngoa ha bonolo ho liprothokholo tsa liteko.Ho feta moo, ho hloeka ha sehlahisoa le ho tsitsa ho tiisa liphetho tse ka hlahisoang, ho e etsa sesebelisoa sa bohlokoa bakeng sa liphetho tse tšepahalang tsa lipatlisiso.
Ha ho tluoa tabeng ea ts'ireletso, re nka mehato e meng le e 'ngoe ea ho etsa bonnete ba hore 17-amino-10-oxy-3,6,12,15-tetraoxa-9-azaheptadecanoic acid e finyella litekanyetso tsa boleng bo phahameng ka ho fetisisa.Mehato e tiileng ea taolo ea boleng e nkoa ho pholletsa le ts'ebetso ea tlhahiso ho netefatsa hore ha ho na litšila kapa litšila.
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